Sunday, August 23, 2015

Voiding dysfunction A Simple Approach Towards Understanding and Management

Voiding dysfunction
A Simple Approach Towards Understanding and Management
by Prof.Dr.Tarek Osman

Tuesday, August 4, 2015

Sexual Intercourse May Clear Distal Ureteral Stones

Yes, it is not a joke. The abstract from pubmed at the end of the page

 Having sex 3-4 times a week was associated with a significantly greater stone passage rate than tamsulosin or standard medical therapy.

    Having sex 3-4 times a week was associated with a significantly greater stone passage rate than tamsulosin or standard medical therapy
Sexual intercourse may be an effective way to clear distal ureteral stones, researchers have concluded.
Omer Gohhan Doluoglu, MD, and colleagues at the Clinic of Ankara Training and Research Hospital in Ankara, Turkey, randomly assigned 90 male patients with distal ureteral stones to 1 of 3 treatment arms: sexual intercourse 3–4 times a week (group 1); tamsulosin 0.4 mg/day (group 2); and standard medical therapy (controls, group 3). The mean stone size was similar among the groups: 4.7, 5.0, and 4.9 mm in groups 1, 2, and 3, respectively. Of the 90 patients, 15 were excluded because of loss to follow-up.
After 2 weeks, 26 (83.9%) of 31 patients in the sexual intercourse group passed their stones compared with 10 (47.6%) of patients in the tamulosin group and 8 (34.8%) of patients in the control arm, according to a report in Urology (2015;86:19-24). The difference in stone passage rate was significantly greater in group 1 versus the other groups.
The mean stone expulsion time was significantly shorter in group 1 compared with the other groups: 10 days in group 1 versus 16.6 days in group 2, and 18 days in group 3.
The investigators postulate that nitric oxide released during erection and sexual intercourse may affect the distal ureters, causing relaxation of ureteral muscle.
"Today, MET [medical expulsive therapy] is recommended as the first-line treatment in ureteral stones that do not necessitate surgery," the authors concluded. "In our opinion, if the patient has a sexual partner, having sexual intercourse at least 3 times a week may be beneficial to increase the probability of spontaneous stone expulsion in patients with distal ureteral stones ≤6 mm in size."
In an accompanying editorial (p.24), Jeffrey J. Tosoian, MD, MPH, of Johns Hopkins Medical Institutions in Baltimore, commented that the study by Dr. Doluoglu's group "has great value in again bringing to light the potential role of the nitric oxide pathway in treatment of stone disease."
Dr. Tosoian cited previous studies that have identified nitrergic fibers in the distal ureter and demonstrated a relaxant effect of nitric oxide on ureteral smooth muscle.

The abstract from Pubmed

 2015 Jul;86(1):19-24. doi: 10.1016/j.urology.2015.03.037.

Can Sexual Intercourse Be an Alternative Therapy for Distal Ureteral Stones? A Prospective, Randomized, Controlled Study.



To investigate the effect of sexual intercourse on spontaneous passage of distal ureteral stones.


The patients were randomly divided into 3 groups with random number table envelope method. Patients in group 1 were asked to have sexual intercourse at least 3-4 times a week. Patients in group 2 were administered tamsulosin 0.4 mg/d. Patients in group 3 received standard medical therapy alone and acted as the controls. The expulsion rate was controlled after 2 and 4 weeks. Differences in the expulsion rate between groups were compared with the chi-square test for 3 × 2 tables. P <.05 was considered as statistically significant.


The mean stone size was 4.7 ± 0.8 mm in group 1, 5 ± 1 mm group 2, and 4.9 ± 0.8 mm group 3 (P = .4). Two weeks later, 26 of 31 patients (83.9%) in the sexual intercourse group, and 10 of 21 patients (47.6%) in tamsulosin group passed their stones, whereas 8 of 23 patients (34.8%) in the control group passed their stones (P = .001). The mean stone expulsion time was 10 ± 5.8 days in group 1, 16.6 ± 8.5 days in group 2, and 18 ± 5.5 days in group 3 (P = .0001).


Our results have indicated that patients who have distal ureteral stones ≤6 mm and a sexual partner may be advised to have sexual intercourse 3-4 times a week to increase the probability of spontaneous passage of the stones.
Copyright © 2015 Elsevier Inc. All rights reserved.

Monday, August 3, 2015

Top 10 Best Android Medical Apps

Article posted originally in
Personally i use Medscape application extensively.... but this is detailed list of other apps...
I will spotlight Medscape app. in separate post... till then enjoy studying on your smartphone

Medical Main
Look in the Google Play Store and you will see that there are hundreds of Android Apps in the Medical category – some Medical Apps are useful for students and professionals in the field and others provide useful information for any individual.  Some Apps are more for educational purposes, others offer how-to-videos, and still others are for first aid – from Babies to Adults. Medical Apps have increased in quality the past couple of years and the ones we suggest here can really provide the user with some quality and helpful information.

My PillBox

My PillBox(Meds&Pill Reminder) Collage
My PillBox – is an application designed for those of us that need to keep track of taking their daily pills.  If you are only taking a couple of pills it is no big problem, but if you are trying to juggling a bunch of pills every day, a pill reminder can be a big help.  This App can also track multiple pill takers, so the entire family can be tracked on just one App.  There are twelve different types of medicine you can categorize, such as: Pills, Capsules, Drops, Injections, Packs and Patches.  You can even choose from nine different colors so it looks like the medicine you are taking.  When you setup a medicine you can add information such as the reason you take it, the date you began taking a medicine, and the doctor that prescribed the medicine.

Home Remedies (Lite)

Home Remedies (Lite) Collage
This is the number one FREE App in Google Play for Home Remedies and is recommended by top U.S. licensed doctors on Health Tap.  The Lite version of this App takes up less memory and has fewer features – if you want the more robust version of the App then purchase the Plus version.  This is the complete guide for home remedies and natural cures for your ailments…they are natural and safe and made from common herbs, spices, fruits and vegetables.

GoodRx Drug Prices and Coupons

GoodRx Drug Prices and Coupons Collage
GoodRx Drug Prices and Coupons – allows you to find the best price for your medicine, offers up coupons, and even gives you directions on Google Maps – you can save 20-80-percent in drug costs.  GoodRx allows you to compare drug prices just as you would plane tickets and covers more than 6,000 drugs at virtually every pharmacy in the U.S. – they only display licensed, legitimate U.S. pharmacies.  GoodRx is completely free and there are no obligations or other hidden costs.
GRAB IT HERE ON GOOGLE PLAY! Medication Guide Medication Guide Collage Medication Guide – easily allows you to look up drug information – you can identify pills, check drug interactions, and keep up your own personal record of medicines that you take.  This App will store a ‘My Drug List’ so you can have instant access to all relevant medical information.  The App contains a Pill Identifier, Interactions Checker, and many more tools that are helpful. is a leader in drug information with over nine million unique visitors each month providing free and informed information.

Visual Anatomy Free

Visual Anatomy Free Collage
Visual Anatomy Free – is an interactive reference and educational tool that now includes a 3D rotational organ model.  There are 58 high-resolution images with more than 300 feature points and the full version has 1247 images.  This App is used primarily as a learning tool but is also useful for physicians to show their patients or students…a great all around general anatomy guide.  You can use Tap and Zoom feature to enlarge any image, use Quick Navigation to jump to other organs, and the App even allows you to take a quiz.

Doctor on Demand

Doctor on Demand Collage
Doctor on Demand – gives you the opportunity to speak to a real doctor or do a video chat online about whatever problem that you are having – all for a $40 fee.  While $40 may be higher than your co-pay, the nice part is you never have to leave your house for a visit and that is certainly worth some money.  You do not have to take time off work, fight through the traffic or sit in a waiting room…definitely a waste of your precious time.  It is designed for more common type of aliments – Cold, Flu, Cough, Fever, Allergies, Prescription Refills, Urinary Tract Infections, STDs and many more.  This service is available where State Laws Permit.

WebMD for Android

WebMD for Android Collage
WebMD for Android – gives you 24/7 access to health information and if you have no internet you can still have access to first aid information.  The App gives you all the decision-making tools and support of WebMD’s Symptom Checker, Drugs and Treatments, First Aid Information, Health Listings, Pill Identification Tool, and Local Health Listings.


CPR•Choking Collage
CPR•Choking – is an App offers instant videos on how to perform CPR and how to help a choking victim.  The App was developed by leading educators and doctors and follows the latest recommendations…From the AHA Executive Summary:
“The newest development in the 2010 AHA Guidelines for CPR and ECC is a change in the basic life support (BLS) sequence of steps from “A-B-C” (Airway, Breathing, Chest compressions) to “C-A-B” (Chest compressions, Airway, Breathing) for adults and pediatric patients (children and infants, excluding newly borns).  Although the experts agreed that it is important to reduce time to first chest compressions, they were aware that a change in something as established as the A-B-C sequence would require re-education of everyone who has ever learned CPR.”

Baby and Child First Aid

Baby and Child First Aid Collage
Baby and Child First Aid – this is the official Red Cross (from Britain) for Infants and Children.  It has useful videos, easy advice, and even a test section – all this free.  As a parent, you need to learn the skills and information that is taught you, prepare yourself for possible emergencies, and test your knowledge.  A must have App if you have any babies or children living with you.

First Aid – American Red Cross

First Aid - American Red Cross Collage
First Aid – American Red Cross – is the definitive App for first aid and a whole lot more.  This App has been reviewed by almost 3900 users and received a 4.7 out of 5 rating, one of the highest I have ever seen and comes with top ratings and has won several awards.  You never know when an accident will happen, but having the ‘Red Cross’ with you can be a big help.  Comes with videos, interactive quizzes, and simple to follow step-by-step instructions.  The App is fully integrated with 9-1-1 so you can call for an EMS from within the App any time.  The App is ad-free and spam-free but does require a SD card with 40MB of free space.

Sunday, August 2, 2015

‘8 reasons I accepted your article'

in this article - on opposite to previous article- an insider from Elsevier reveals 8 reasons for article acceptance from point of view of 5 editors-in-chief.

Journal editors reveal the top reasons a manuscript gets published

By Elizabeth Zwaaf     a Marketing Communications Specialist at Elsevier. 

At Elsevier, it's the responsibility of every editor-in-chief to maintain and develop their journal's profile and reputation. The editor also has the final responsibility for content, ensuring that it meets the aims and scope of the journal and reflects changes in the field by presenting new and emerging research.
In September, Elsevier Connect published an article by Dr. Peter Thrower, Editor-in-Chief of Carbon, called "8 reasons I rejected your article." Because of the article's popularity, we followed up by asking five of our editors a related question: What are the top eight reasons you accept a paper? They all came up with similar reasons, which we present here along with their commentary.
The eight reasons are summed up by Dr. Torsten Pieper, Assistant Editor of the Journal of Family Business Strategy and Assistant Professor at the Cox Family Enterprise Center, Coles College of Business, at Kennesaw State University in Georgia, and his colleague, Dr. Joseph Astrachan, Editor-in-Chief of the journal and Executive Director of the Cox Family Enterprise Center and Professor of Management and Entrepreneurship.
1. It provides insight into an important issue – for example, by explaining a wide variance when numbers are spread out from the mean or expected value, or by shedding light on an unsolved problem that affects a lot of people.
2. The insight is useful to people who make decisions, particularly long-term organizational decisions or, in our particular field, family decisions.
3. The insight is used to develop a framework or theory, either a new theory or advancing an existing one.
4. The insight stimulates new, important questions.
5. The methods used to explore the issue are appropriate (for example, data collection and analysis of data).
6. The methods used are applied rigorously and explain why and how the data support the conclusions.
7. Connections to prior work in the field or from other fields are made and serve to make the article's arguments clear.
8. The article tells a good story, meaning it is well written and easy to understand, the arguments are logical and not internally contradictory.
"Ideally, we would like to see articles perform well on all eight points, and that the author strives for a good balance amongst these criteria," said Dr. Pieper said.

'Show me something new'

For Dr. Alexander T. Florence, Editor-in-Chief of the International Journal of Pharmaceutics and Professor Emeritus at University College London, whether he passes a paper on to the referees for peer review is partly determined "not by hard and fast rules but by my own feeling.
"For the subject, it is what I have seen over the years in the journal and what I feel is current, novel and not derivative," he said.
Professor Florence added that he is intrigued by work that is very new and by papers he wishes he thought about doing himself. After the paper has survived reviewer scrutiny, Dr. Florence said, it helps when the reviewers are unanimous in their views. While the reviewing process is very strict, reviewers might be split on their final decision: for example, one might recommend "rejection,"  another "major revision" and the third "accept as is."

Loren E. Wold, PhDLoren E. Wold, PhD
For Dr. Loren E. Wold , Executive Editor-in-Chief of Life Sciences and Principal Investigator of the Center for Cardiovascular and Pulmonary Research of the Research Institute at Nationwide Children's Hospital in Columbus, Ohio, "Acceptance is contingent upon whether an  article advances our understanding of a topic, what is beyond already known, and opens up a new arena.

"What we are seeing in Life Sciences, as well as other journals, is the explosive growth of new technology which has broad implications on these studies," he said.

Do your own work

While a paper might "tick all the boxes," the question on everyone's mind is, "Is it original?" With the increasing use of technology — and several software programs now available to detect plagiarism, such as CrossCheck — the paper's originality can be easily determined and detected before the referees see it. At Elsevier, many papers undergo this scrutiny.
While plagiarism is not a crime per se, it is considered a moral offense and can involve liability for copyright infringement.
"There should be no hints of plagiarism or fabrication in the paper," said Dr. Francesco Visioli, Editor-in-Chief of Pharmacological Research and the recently launched journal PharmaNutrition. Also, he added, "data in the figures should match those reported in the results, and the results are not in contradiction with each other."

Use varied research methods

Dr. Pieper, who moved from Germany to the US about five years ago, looks at the type of research submitted from different parts of the world. "Moving from Europe to the US, I see there is a marked difference between the output of US researchers compared to their European counterparts in qualitative as opposed to quantitative research for my family of journals," he said, pointing out that well over 75 percent of submissions coming from the US use quantitative methods compared to about 50 percent from Europe.
"This clearly demonstrates to me that European researchers are more embracing of alternative methods to explore a phenomenon of interest," he said. "Going forward, I would like to see a more even balance in the papers submitted from the US."

Resources for authors

Before submitting a paper, authors should study the journal's aims and scope and consult with the Guide for Authors.
For more advice, check out the step-by-step guide How to publish in an Elsevier Journal and the Publishing Connect Author Training Webcasts.
For information on the Elsevier's online submission system, visit the Elsevier Editorial System (EES) customer support site at

Saturday, August 1, 2015

Eight reasons I rejected your article

Peter Thrower, is telling you, in a simple way, 8 reasons of paper rejection
This article is recommended for reading before applying manuscript to European Urology Journal

Eight reasons I rejected your article
Peter Thrower, PhD

When a manuscript is submitted to a high-quality scholarly journal, it goes through intense scrutiny  — even before it's seen by the editor-in-chief and selected for peer review. At Elsevier, between 30 percent to 50 percent of articles don't even make it to the peer review process.
As Editor-in-Chief of Carbonthe international journal of the American Carbon Society, Dr. Peter Thrower experiences this situation first-hand. His advice to authors: "By avoiding these pitfalls, you will save reviewers, editors and staff time and frustration, and ensure that your work is judged by its scientific merit, not mistakes."

1. It fails the technical screening.

Before they even go to the editor-in-chief, articles are checked for technical elements. The main reasons they are rejected are:
Peter Thrower, PhD, is Editor-in-Chief of Carbon, the international journal of the American Carbon Society, and Professor Emeritus of Material Sciences and Engineering at Penn State University.
  • The article contains elements that are suspected to be plagiarized, or it is currently under review at another journal. (Republishing articles or parts of articles, submitting to one or more journals at the same time or using text or images without permission is not allowed. See our ethical guidelines.)
  • The manuscript is not complete; it may be lacking key elements such as the title, authors, affiliations, keywords, main text, references and all tables and figures).
  • The English is not sufficient for the peer review process,
  • The figures are not complete or are not clear enough to read.
  • The article does not conform to the Guide for Authors for the journal it is submitted to.
  • References are incomplete or very old.

2.  It does not fall within the Aims and Scope.

  • For the journal Carbon, the material studied may contain carbon, but is not carbon.
  • The study uses a carbon material but the focus is on something different.
  • There is no new carbon science.

3.  It's incomplete.

  • The article contains observations but is not a full study.
  • It discusses findings in relation to some of the work in the field but ignores other important work.

4.  The procedures and/or analysis of the data is seen to be defective.

  • The study lacked clear control groups or other comparison metrics.
  • The study did not conform to recognized procedures or methodology that can be repeated.
  • The analysis is not statistically valid or does not follow the norms of the field.

5.  The conclusions cannot be justified on the basis of the rest of the paper.

  • The arguments are illogical, unstructured or invalid.
  • The data does not support the conclusions.
  • The conclusions ignore large portions of the literature.

6.  It's is simply a small extension of a different paper, often from the same authors.

  • Findings are incremental and do not advance the field.
  • The work is clearly part of a larger study, chopped up to make as many articles as possible.

7.  It's incomprehensible.

  • The language, structure, or figures are so poor that the merit can't be assessed. Have a native English speaker read the paper. Even if you ARE a native English speaker. Need help? We offer language services.

8.  It's boring.

  • It is archival, incremental or of marginal interest to the field (see point 6).
  • The question behind the work is not of interest in the field.
  • The work is not of interest to the readers of the specific journals.

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