Tuesday, December 17, 2013

How does Neuromodulation work? part 1

          The bladder and pelvic floor receive most of their innervations from the pudendal nerve, with 70% coming from the S3 nerve root and 30% from S2 and possibly S4. 
              Sacral parasympathetic preganglionic fibers in the pelvic nerve provide the major excitatory input to the bladder. 
               Fibers originating in the thoracolumbar sympathetic pathways provide the inhibitory input. 
              Afferent pelvic pathways are composed of small, myelinated A fibers and unmyelinated C-fibers. 

              These pathways, transmitting signals from the bladder mechanoreceptors, pelvic visceral organs, and somatic pathways, provide signals for the voluntary control of micturition.



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