Wednesday, May 23, 2012

Solabegron Safe and Effective in Overactive Bladder

Smooth muscle relaxation during bladder filling is mediated by beta-adrenergic receptors, predominantly of the beta-3 subtype in humans. Agonists of this receptor can be effective in the treatment of urinary frequency, urgency, and urgency incontinence. Solabegron is a highly selective high-affinity beta-3 adrenoceptor agonist currently in clinical development for the treatment of OAB symptoms.



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