NBI cystoscopy resulted in significantly improved CIS,
pTa, and overall NMIBT detection rates compared with
WLC in cases of large bladder tumors. Also, BPV showed
a superior safety profile compared with monopolar
TURBT and significantly decreased postoperative recovery.
Using this combined technique, significantly lower
overall NMIBT, initial multiple, Stage pT1, and primary
site residual tumor rates were found compared with standard
repeat TUR. During the follow-up period, significantly
reduced overall NMIBT, initial multiple, and
other site 1-year recurrence rates were described for those
who initially underwent NBI and BPV.
This new diagnostic and treatment approach seems to
represent a viable alternative for endoscopic treatment of
large NMIBTs and is apparently able to challenge the
reference standard status of WLC and monopolar
TURBT and to bring significant improvements to bladder
cancer therapeutic management.
UROLOGY 79: 846–852, 2012.