Sunday, April 15, 2012

The Contemporary Role of Lymph Node Dissection During Nephroureterectomy in the Management of Upper Urinary Tract Urothelial Carcinoma: The Canadian Experience


Nodal disease is associated with a decreased survival in
patients undergoing nephroureterectomy for upper urinary
tract urothelial carcinoma. An increase in the ratio
of positive nodes to nodes removed among patients undergoing
nephroureterectomy was associated with a decreased
OS, DSS, and RFS, whereas the number of positive
nodes and the total number of nodes removed did
not predict survival. LND during nephroureterectomy
allows more accurate staging and prediction of survival,
but it remains uncertain whether LND independently
improves survival in patients with UTUC.





overall survival (OS), disease-specific survival (DSS), and recurrence-free
survival (RFS)

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